Dr. Natalie Crawford, board certified OBGYN and REI, discusses the impact of marijuana and getting pregnant and fertility outcomes. Cannabis use can impact sperm production and male hormones (testosterone), decrease ovarian reserve and ovulation, decrease the chance of live birth naturally and with IVF. Miscarriage rates are higher in women who use marijuana and pregnancy complications, including increased chance of placental issues and neonatal death, are more prevalent in women who report positive marijuana exposure.

Covered in this video:
Sperm and testosterone
Eggs and ovarian reserve
Ovulation
Natural fertility
Live birth
In vitro fertilization (IVF) outcomes
Placental dysfunction
Miscarriage
Neonatal morbidity and death

Resources:
Mumford SL. Cannabis use while trying to conceive: a prospective cohort study evaluating associations with fecundability, live birth and pregnancy loss. Hum Reprod. 2021 Jan 9:deaa355. doi: 10.1093/humrep/deaa355. Epub ahead of print. PMID: 33421071.

Nassan FL,. EARTH Study Team. Marijuana smoking and outcomes of infertility treatment with assisted reproductive technologies. Hum Reprod. 2019 Sep 29;34(9):1818-1829. doi: 10.1093/humrep/dez098. PMID: 31505640; PMCID: PMC6736415.

Neradugomma NK. Marijuana-derived cannabinoids inhibit uterine endometrial stromal cell decidualization and compromise trophoblast-endometrium cross-talk. Reprod Toxicol. 2019 Aug;87:100-107. doi: 10.1016/j.reprotox.2019.05.064. Epub 2019 May 30. PMID: 31154070; PMCID: PMC6613995.

Goldenberg RL. Maternal marijuana use, adverse pregnancy outcomes, and neonatal morbidity. Am J Obstet Gynecol. 2017 Oct;217(4):478.e1-478.e8. doi: 10.1016/j.ajog.2017.05.050. Epub 2017 May 31. PMID: 28578174; PMCID: PMC5614818.

Nassan FL. EARTH Study Team. Marijuana smoking and markers of testicular function among men from a fertility centre. Hum Reprod. 2019 Apr 1;34(4):715-723. doi: 10.1093/humrep/dez002. PMID: 30726923; PMCID: PMC6443114.

du Plessis SS. Marijuana, phytocannabinoids, the endocannabinoid system, and male fertility. J Assist Reprod Genet. 2015 Nov;32(11):1575-88. doi: 10.1007/s10815-015-0553-8. Epub 2015 Aug 16. PMID: 26277482; PMCID: PMC4651943.

Payne KS. Cannabis and Male Fertility: A Systematic Review. J Urol. 2019 Oct;202(4):674-681. doi: 10.1097/JU.0000000000000248. Epub 2019 Sep 6. PMID: 30916627; PMCID: PMC7385722.

Carroll K. Marijuana use and its influence on sperm morphology and motility: identified risk for fertility among Jamaican men. Andrology. 2020 Jan;8(1):136-142. doi: 10.1111/andr.12670. Epub 2019 Jul 2. PMID: 31267718.

Kolodny RC. Depression of plasma testosterone levels after chronic intensive marihuana use. N Engl J Med  1974;290:872–874.

Kharbanda EO. Birth and early developmental screening outcomes associated with cannabis exposure during pregnancy. J Perinatol. 2020 Mar;40(3):473-480. doi: 10.1038/s41372-019-0576-6. Epub 2020 Jan 7. PMID: 31911642; PMCID: PMC7047636.

Corsi DJ. Association Between Self-reported Prenatal Cannabis Use and Maternal, Perinatal, and Neonatal Outcomes. JAMA. 2019 Jul 9;322(2):145-152. doi: 10.1001/jama.2019.8734. PMID: 31211826; PMCID: PMC6582262.

Sun AJ. Association between marijuana use and sexual frequency in the United States: a population-based study. J Sex Med  2017;14:1342–1347.

*The information in this video is educational. Please contact your doctor for any direct medical advice.
———-
Dr. Natalie Crawford, MD is a double board certified OBGYN and REI, and co-founder of Fora Fertility, a boutique fertility practice in Austin, Texas.

Welcome to the “As a Woman” community where we are all stronger together.

COME SAY HI!!!
Blog: nataliecrawfordmd.com
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Facebook: https://www.facebook.com/nataliecrawfordmd/
Email: hello@nataliecrawfordmd.com

FORA FERTILITY:
forafertilityaustin.com
715 W 34th Street, Austin, TX 78705
To become a patient: email info@forafertilityaustin.com or call 512-956-5006

Listen to the AS A WOMAN PODCAST here:
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———-
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Sharing fertility facts to educate women about trying to conceive, getting pregnant, ovulation, fertility treatments, IUI, IVF, becoming a doctor, life as a woman in medicine, and more.

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